The state of dermis determines the elasticity and firmness of our skin. Since active agents usually cannot penetrate
into the dermis, sNGF-creams follow an entirely new strategy: cell communication.
Cell communication
In the function and operation of the communication between the outer and inner skin layer is thereby taken advantage of, that is, the communication of cells of the epidermis (the epidermis) to the cells of the dermis (dermis). Important for the formation of new collagen and elastin are thereby growth factors. Keratinocytes (horny cells of the top layer of skin) are stimulated so that they make and distribute messengers - growth factors, cytokines. The messengers then penetrate the epidermis (upper skin layer) into the dermis (corium). This way they can reach the fibroblasts, where they connect to specific receptors of the cell surface, and then forward the signal for the formation of collagen and elastin to the cell nuclei.